New Zampanolide Mimics: Design, Synthesis, and Antiproliferative Evaluation
Zampanolide is a promising microtubule-stabilizing agent (MSA) with a unique chemical structure. It is superior to the current clinically used MSAs due to the covalent nature of its binding to <i>β</i>-tubulin and high cytotoxic potency toward multidrug-resistant cancer cells. H...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-01-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/2/362 |