Compartmental architecture and dynamics of hematopoiesis.

BACKGROUND: Blood cell formation is maintained by the replication of hematopoietic stem cells (HSC) that continuously feed downstream "compartments" where amplification and differentiation of cells occurs, giving rise to all blood lineages. Whereas HSC replicate slowly, committed cells rep...

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Bibliographic Details
Main Authors: David Dingli, Arne Traulsen, Jorge M Pacheco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1828630?pdf=render