A Francisella novicida Mutant, Lacking the Soluble Lytic Transglycosylase Slt, Exhibits Defects in Both Growth and Virulence

A Francisella novicida Mutant, Lacking the Soluble Lytic Transglycosylase Slt, Exhibits Defects in Both Growth and Virulence

Francisella tularensis is the causative agent of tularemia and has gained recent interest as it poses a significant biothreat risk. F. novicida is commonly used as a laboratory surrogate for tularemia research due to genetic similarity and susceptibility of mice to infection. Currently, there is no...

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Bibliographic Details
Main Authors: Beth A. Bachert, Sergei S. Biryukov, Jennifer Chua, Sabrina A. Rodriguez, Ronald G. Toothman, Christopher K. Cote, Christopher P. Klimko, Melissa Hunter, Jennifer L. Shoe, Janice A. Williams, Kathleen A. Kuehl, Fabrice V. Biot, Joel A. Bozue
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Microbiology
Subjects:
Francisella
peptidoglycan (PG)
tularemia
Francisella novicida
virulence
cell morphology
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01343/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.01343/full

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