Role of microRNA 690 in Mediating Angiotensin II Effects on Inflammation and Endoplasmic Reticulum Stress

Role of microRNA 690 in Mediating Angiotensin II Effects on Inflammation and Endoplasmic Reticulum Stress

Overactivation of the renin–angiotensin system (RAS) during obesity disrupts adipocyte metabolic homeostasis and induces endoplasmic reticulum (ER) stress and inflammation; however, underlying mechanisms are not well known. We propose that overexpression of angiotensinogen (Agt), the precursor prote...

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Bibliographic Details
Main Authors: Kalhara R. Menikdiwela, Latha Ramalingam, Mostafa M. Abbas, Halima Bensmail, Shane Scoggin, Nishan S. Kalupahana, Asha Palat, Preethi Gunaratne, Naima Moustaid-Moussa
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
adipocytes
renin–angiotensin system (RAS)
obesity
miR-690
endoplasmic reticulum (ER) stress
inflammation
Online Access:https://www.mdpi.com/2073-4409/9/6/1327

Internet

https://www.mdpi.com/2073-4409/9/6/1327

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