Kaempferol protects mice from d-GalN/LPS-induced acute liver failure by regulating the ER stress-Grp78-CHOP signaling pathway

Kaempferol protects mice from d-GalN/LPS-induced acute liver failure by regulating the ER stress-Grp78-CHOP signaling pathway

Kaempferol is a flavonoid compound that has many functions, such as anti-inflammation and antioxidation. Acute liver failure (ALF) is a life-threatening illness accompanied by serious inflammation and extensive hepatocyte apoptosis. The aim of this study was to examine the therapeutic potential of k...

Full description

Bibliographic Details
Main Authors: Huijuan Wang, Liyan Chen, Xiangying Zhang, Lin Xu, Bangxiang Xie, Hongbo Shi, Zhongping Duan, Huanhu Zhang, Feng Ren
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Kaempferol
Acute liver failure
ER stress
Apoptosis
Grp78
CHOP
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218374912

Internet

http://www.sciencedirect.com/science/article/pii/S0753332218374912

Similar Items