Modeling Microenvironmental Regulation of Glioblastoma Stem Cells: A Biomaterials Perspective
Following diagnosis of a glioblastoma (GBM) brain tumor, surgical resection, chemotherapy, and radiation together yield a median patient survival of only 15 months. Importantly, standard treatments fail to address the dynamic regulation of the brain tumor microenvironment that actively supports tumo...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-02-01
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Series: | Frontiers in Materials |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fmats.2018.00007/full |