Modeling Microenvironmental Regulation of Glioblastoma Stem Cells: A Biomaterials Perspective

Following diagnosis of a glioblastoma (GBM) brain tumor, surgical resection, chemotherapy, and radiation together yield a median patient survival of only 15 months. Importantly, standard treatments fail to address the dynamic regulation of the brain tumor microenvironment that actively supports tumo...

Full description

Bibliographic Details
Main Authors: John M. Heffernan, Rachael W. Sirianni
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Materials
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmats.2018.00007/full