Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized rats.

Angiopoietin (Angpt)-2, a permeability-increasing growth factor, is involved in vascular leakage of sepsis and acute lung injury, and could be released from endothelium in response to anaphylaxis-related secretagogues such as histamine and leukotrienes, or cytokines. However, roles of Angpt-2 in the...

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Bibliographic Details
Main Authors: Tao Zhang, Toshishige Shibamoto, Mamoru Tanida, Makoto Taniguchi, Yuhichi Kuda, Wei Yang, Yasutaka Kurata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242026