Allele-level haplotype frequencies and pairwise linkage disequilibrium for 14 KIR loci in 506 European-American individuals.

The immune responses of natural killer cells are regulated, in part, by killer cell immunoglobulin-like receptors (KIR). The 16 closely-related genes in the KIR gene system have been diversified by gene duplication and unequal crossing over, thereby generating haplotypes with variation in gene copy...

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Main Authors: Cynthia Vierra-Green, David Roe, Lihua Hou, Carolyn Katovich Hurley, Raja Rajalingam, Elaine Reed, Tatiana Lebedeva, Neng Yu, Mary Stewart, Harriet Noreen, Jill A Hollenbach, Lisbeth A Guethlein, Tao Wang, Stephen Spellman, Martin Maiers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3489906?pdf=render