Overcoming TRAIL-resistance by sensitizing prostate cancer 3D spheroids with taxanes.

Three-dimensional spheroid cultures have been shown to better physiologically mimic the cell-cell and cell-matrix interactions that occur in solid tumors more than traditional 2D cell cultures. One challenge in spheroid production is forming and maintaining spheroids of uniform size. Here, we develo...

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Bibliographic Details
Main Authors: Korie A Grayson, Nidhi Jyotsana, Nerymar Ortiz-Otero, Michael R King
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0246733