Renoprotective Action of a Matrix Metalloproteinase Inhibitor in Progressive Mesangioproliferative Nephritis
Background/Aim: Matrix metalloproteinases (MMPs) play pivotal roles in extracellular matrix turnover and are involved in chronic kidney disease. The renoprotective action of a synthetic MMP inhibitor, compound A, was investigated in chronic nephritis. Methods: Nephritis was induced by a single injec...
Main Authors: | Takayuki Kuroda, Masao Masui, Mitsuru Notoya, Masashi Ito, Yoshinori Tamura, Hiroyuki Okamoto, Eri Kanaoka, Toshihiro Shinosaki |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2012-05-01
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Series: | Nephron Extra |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/338801 |
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