Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs).

Recent generation of patient-specific induced pluripotent stem cells (PS-iPSCs) provides significant advantages for cell- and gene-based therapy. Establishment of iPSC-based therapy for skin diseases requires efficient methodology for differentiating iPSCs into both keratinocytes and fibroblasts, th...

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Bibliographic Details
Main Authors: Munenari Itoh, Noriko Umegaki-Arao, Zongyou Guo, Liang Liu, Claire A Higgins, Angela M Christiano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795682?pdf=render