Preliminary Safety Assessment of New Azinesulfonamide Analogs of Aripiprazole using Prokaryotic Models

Preliminary Safety Assessment of New Azinesulfonamide Analogs of Aripiprazole using Prokaryotic Models

Purpose: Determination of the mutagenic potential of new biologically active compounds is of great concern for preliminary toxicity testing and drug development. Methods: The mutagenic and antimutagenic effects of some quinoline- and isoquinoline-sulfonamide analogs of aripiprazole (1-8), which dis...

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Bibliographic Details
Main Authors: Beata Powroźnik, Karolina Słoczyńska, Krzysztof Marciniec, Paweł Zajdel, Elżbieta Pękala
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2016-09-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Ames test
Antimutagenicity
Aripiprazole
Isoquinoline-sulfonamides
Quinoline-sulfonamides
Vibrio harveyi assay
Online Access:http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-377.pdf

Internet

http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-377.pdf

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