Functional plasticity in the type IV secretion system of Helicobacter pylori.

Helicobacter pylori causes clinical disease primarily in those individuals infected with a strain that carries the cytotoxin associated gene pathogenicity island (cagPAI). The cagPAI encodes a type IV secretion system (T4SS) that injects the CagA oncoprotein into epithelial cells and is required for...

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Bibliographic Details
Main Authors: Roberto M Barrozo, Cara L Cooke, Lori M Hansen, Anna M Lam, Jennifer A Gaddy, Elizabeth M Johnson, Taryn A Cariaga, Giovanni Suarez, Richard M Peek, Timothy L Cover, Jay V Solnick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3585145?pdf=render