The Dishevelled, EGL-10 and pleckstrin (DEP) domain-containing protein DEPDC7 binds to CARMA2 and CARMA3 proteins, and regulates NF-κB activation.

The Dishevelled, EGL-10 and pleckstrin (DEP) domain-containing protein DEPDC7 binds to CARMA2 and CARMA3 proteins, and regulates NF-κB activation.

The molecular complexes containing BCL10, MALT1 and CARMA proteins (CBM complex) have been recently identified as a key component in the signal transduction pathways that regulate activation of Nuclear Factor kappaB (NF-κB) transcription factor. Herein we identified the DEP domain-containing protein...

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Bibliographic Details
Main Authors: Egildo Luca D'Andrea, Angela Ferravante, Ivan Scudiero, Tiziana Zotti, Carla Reale, Maddalena Pizzulo, Luigi Regenburgh De La Motte, Chiara De Maio, Pellegrino Mazzone, Gianluca Telesio, Pasquale Vito, Romania Stilo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4277425?pdf=render

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http://europepmc.org/articles/PMC4277425?pdf=render

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