Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach

Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach

Abstract Identification of small molecules with the potential to selectively proliferate cardiac progenitor cells (CPCs) will aid our understanding of the signaling pathways and mechanisms involved and could ultimately provide tools for regenerative therapies for the treatment of post‐MI cardiac dys...

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Bibliographic Details
Main Authors: Lauren Drowley, Jane McPheat, Anneli Nordqvist, Samantha Peel, Ulla Karlsson, Sofia Martinsson, Erik Müllers, Anita Dellsén, Sinead Knight, Ian Barrett, José Sánchez, Björn Magnusson, Boris Greber, Qing‐Dong Wang, Alleyn T. Plowright
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Stem Cells Translational Medicine
Subjects:
cell proliferation
gene expression
high throughput screening assays
induced pluripotent stem cells
nuclear receptors
small molecule libraries
Online Access:https://doi.org/10.1002/sctm.19-0069

Internet

https://doi.org/10.1002/sctm.19-0069

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