A balance of BMP and notch activity regulates neurogenesis and olfactory nerve formation.

Although the function of the adult olfactory system has been thoroughly studied, the molecular mechanisms regulating the initial formation of the olfactory nerve, the first cranial nerve, remain poorly defined. Here, we provide evidence that both modulated Notch and bone morphogenetic protein (BMP)...

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Bibliographic Details
Main Authors: Esther Maier, Hanna Nord, Jonas von Hofsten, Lena Gunhaga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3044177?pdf=render