Interleukin-35 modulates the balance between viral specific CD4+CD25+CD127dim/- regulatory T cells and T helper 17 cells in chronic hepatitis B virus infection

Interleukin-35 modulates the balance between viral specific CD4+CD25+CD127dim/- regulatory T cells and T helper 17 cells in chronic hepatitis B virus infection

Abstract Background Interleukin (IL)-35 regulates imbalance between regulatory T cells (Tregs) and T helper (Th) 17 cells, leading to an important modulator in autoimmune disorder, cancer, and infectious diseases. Our previous study revealed an immunosuppressive activity of IL-35 in chronic hepatiti...

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Bibliographic Details
Main Authors: Lanlan Yang, Shengnan Jia, Xue Shao, Siqi Liu, Qian Zhang, Jie Song, Wudong Wang, Zhenjing Jin
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Virology Journal
Subjects:
Interleukin-35
Regulatory T cells
T helper 17 cells
Hepatitis B virus
Online Access:http://link.springer.com/article/10.1186/s12985-019-1158-0

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http://link.springer.com/article/10.1186/s12985-019-1158-0

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