Characterization of MED12, HMGA2, and FH alterations reveals molecular variability in uterine smooth muscle tumors

Characterization of MED12, HMGA2, and FH alterations reveals molecular variability in uterine smooth muscle tumors

Abstract Uterine smooth muscle tumors range from benign leiomyomas to malignant leiomyosarcomas. Based on numerous molecular studies, leiomyomas and leiomyosarcomas mostly lack shared mutations and the majority of tumors are believed to develop through distinct mechanisms. To further characterize th...

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Bibliographic Details
Main Authors: Netta Mäkinen, Kati Kämpjärvi, Norma Frizzell, Ralf Bützow, Pia Vahteristo
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Molecular Cancer
Subjects:
Uterine leiomyoma
Histopathological uterine leiomyoma variants
Uterine leiomyosarcoma
MED12
HMGA2
FH
Online Access:http://link.springer.com/article/10.1186/s12943-017-0672-1

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http://link.springer.com/article/10.1186/s12943-017-0672-1

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