The IL-1RI Co-Receptor TILRR (FREM1 Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease
Expression of the interleukin-1 receptor type I (IL-1RI) co-receptor Toll-like and interleukin-1 receptor regulator (TILRR) is significantly increased in blood monocytes following myocardial infarction and in the atherosclerotic plaque, whereas levels in healthy tissue are low. TILRR association wit...
Main Authors: | Sarah A. Smith, PhD, Andriy O. Samokhin, PhD, Mabruka Alfadi, PhD, Emer C. Murphy, PhD, David Rhodes, MSc, W. Mike L. Holcombe, PhD, Endre Kiss-Toth, PhD, Robert F. Storey, BSc, BM, DM, Siu-Pok Yee, PhD, Sheila E. Francis, PhD, Eva E. Qwarnstrom, PhD |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2017-08-01
|
Series: | JACC: Basic to Translational Science |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2452302X1730133X |
Similar Items
-
Bioinformatics Analysis of the FREM1 Gene—Evolutionary Development of the IL-1R1 Co-Receptor, TILRR
by: Eva E. Qwarnstrom, et al.
Published: (2012-09-01) -
The Potential Role of FREM1 and Its Isoform TILRR in HIV-1 Acquisition through Mediating Inflammation
by: Mohammad Abul Kashem, et al.
Published: (2021-07-01) -
TILRR Steers Interleukin-1 Signaling
by: Feilim Mac Gabhann, PhD
Published: (2017-08-01) -
Effects of vitamin E supplementation on activity of serum Paraoxonase, SOD, GPX enzymes and lipid profiles in beta major thalassemia patients
by: Aboomardani M (PhD), et al.
Published: (2012-01-01) -
Losartan protects against osteoarthritis by repressing the TGF-β1 signaling pathway via upregulation of PPARγ
by: Zhenhan Deng, MD, Ph.D, et al.
Published: (2021-07-01)