Generation of induced pluripotent stem cells from a patient with Parkinson's disease carrying LRRK2 p.I2012T mutation

Generation of induced pluripotent stem cells from a patient with Parkinson's disease carrying LRRK2 p.I2012T mutation

Parkinson's disease (PD) is a progressive neurodegenerative disorder caused by interactions between genetic and environmental factors. Leucine rich repeat kinase (LRRK2) is the most prevalent mutation in autosomal-dominant inheritance of PD. Here, we generated induced pluripotent stem cells (iP...

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Bibliographic Details
Main Authors: Chin-Hsien Lin, Yu-Che Cheng, Han-I Lin, Ming-Ching Ho, Yu-Hung Hsu, Cheng-Hao Wen, Hui-Wen Ko, Huai-En Lu, Ching-Ying Huang, Patrick C.H. Hsieh
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117302222

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http://www.sciencedirect.com/science/article/pii/S1873506117302222

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