Increased Legumain/Smad3 expression in atherosclerotic plaque of rat thoracic aorta

Objectives: The purpose of this study was to investigate the role of legumain in the formation and stability of atherosclerotic plaque, as well as to explore the association between legumain with Smad3 pathway in a rat atherosclerosis model. Methods: Rat with thoracic aorta atherosclerosis was estab...

Full description

Bibliographic Details
Main Authors: Yeqing Fang, Chengcheng Duan, Shaoyuan Chen, Peiyi Xie, Wen Ai, Lei Wang, Rongzhi Liu, Hongcheng Fang
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219308649