Natural Antibodies Prevent in Vivo Transmission of Porcine Islet-Derived Endogenous Retrovirus to Human Cells

The discovery of porcine endogenous retroviruses (PERV) has raised concerns regarding the safety of porcine xenotransplantation. However, transmission of PERV had not been observed in humans exposed to porcine tissue. We examined whether PERV derived from porcine pancreatic islet cells could infect...

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Bibliographic Details
Main Authors: Brice W. Mckane, Sabarinathan Ramachandran, Xiao-Chun Xu, Barbara J. Olack, William C. Chapman, T. Mohanakumar Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2004-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000004773301816