Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression

Summary: We have established experimental systems to assess the effects of early-life exposures to antibiotics on the intestinal microbiota and gene expression in the brain. This model system is highly relevant to human exposure and may be developed into a preclinical model of neurodevelopmental dis...

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Bibliographic Details
Main Authors: Angelina Volkova, Kelly Ruggles, Anjelique Schulfer, Zhan Gao, Stephen D. Ginsberg, Martin J. Blaser
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221007653