Specific roles of Akt iso forms in apoptosis and axon growth regulation in neurons.

Akt is a member of the AGC kinase family and consists of three isoforms. As one of the major regulators of the class I PI3 kinase pathway, it has a key role in the control of cell metabolism, growth, and survival. Although it has been extensively studied in the nervous system, we have only a faint k...

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Bibliographic Details
Main Authors: Hector Diez, Juan Jose Garrido, Francisco Wandosell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3324480?pdf=render