Eco-Friendly Synthesis, Biological Evaluation, and In Silico Molecular Docking Approach of Some New Quinoline Derivatives as Potential Antioxidant and Antibacterial Agents

Eco-Friendly Synthesis, Biological Evaluation, and In Silico Molecular Docking Approach of Some New Quinoline Derivatives as Potential Antioxidant and Antibacterial Agents

A new series of quinoline derivatives 5–12 were efficiently synthesized via one-pot multicomponent reaction (MCR) of resorcinol, aromatic aldehydes, β-ketoesters, and aliphatic/aromatic amines under solvent-free conditions. All products were obtained in excellent yields, pure at low-cost processing,...

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Bibliographic Details
Main Authors: Ahmed M. El-Saghier, Mohamed El-Naggar, Abdel Haleem M. Hussein, Abu-Bakr A. El-Adasy, M. Olish, Aboubakr H. Abdelmonsef
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Chemistry
Subjects:
multicomponent reaction
chromenoquinolines
antioxidant
antibacterial
molecular docking
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2021.679967/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2021.679967/full

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