Novel Prognostic Biomarkers in Metastatic and Locally Advanced Colorectal Cancer: Micronuclei Frequency and Telomerase Activity in Peripheral Blood Lymphocytes

Novel Prognostic Biomarkers in Metastatic and Locally Advanced Colorectal Cancer: Micronuclei Frequency and Telomerase Activity in Peripheral Blood Lymphocytes

PurposeDue to the current practice on colorectal cancer (CRC) management, chemoresistance is most often recognized at the end of the treatment. Therefore, effective and easy-to-use prognostic biomarkers are needed.Experimental DesignWe evaluated the prognostic significance of two novel CRC biomarker...

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Bibliographic Details
Main Authors: Taxiarchis Konstantinos Nikolouzakis, Elena Vakonaki, Polychronis D. Stivaktakis, Athanasios Alegakis, Aikaterini Berdiaki, Nikolaos Razos, John Souglakos, Aristidis Tsatsakis, John Tsiaoussis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
metastatic colorectal cancer
locally advanced rectal cancer
micronuclei frequency
telomerase activity
biomarkers
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.683605/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.683605/full

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