Ferricytochrome (c) directly oxidizes aminoacetone to methylglyoxal, a catabolite accumulated in carbonyl stress.

Ferricytochrome (c) directly oxidizes aminoacetone to methylglyoxal, a catabolite accumulated in carbonyl stress.

Age-related diseases are associated with increased production of reactive oxygen and carbonyl species such as methylglyoxal. Aminoacetone, a putative threonine catabolite, is reportedly known to undergo metal-catalyzed oxidation to methylglyoxal, NH4(+) ion, and H2O2 coupled with (i) permeabilizatio...

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Bibliographic Details
Main Authors: Adriano Sartori, Camila M Mano, Mariana C Mantovani, Fábio H Dyszy, Júlio Massari, Rita Tokikawa, Otaciro R Nascimento, Iseli L Nantes, Etelvino J H Bechara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23483930/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23483930/pdf/?tool=EBI

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