Convergent evolution involving dimeric and trimeric dUTPases in pathogenicity island mobilization.

The dUTPase (Dut) enzymes, encoded by almost all free-living organisms and some viruses, prevent the misincorporation of uracil into DNA. We previously proposed that trimeric Duts are regulatory proteins involved in different cellular processes; including the phage-mediated transfer of the Staphyloc...

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Bibliographic Details
Main Authors: Jorge Donderis, Janine Bowring, Elisa Maiques, J Rafael Ciges-Tomas, Christian Alite, Iltyar Mehmedov, María Angeles Tormo-Mas, José R Penadés, Alberto Marina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006581