Shared associations identify causal relationships between gene expression and immune cell phenotypes
Christiane Gasperi et al. used a shared association mapping approach to identify pairs of immune cell traits and gene expression traits showing shared genetic associations. Using polygenic risk score analysis and Mendelian randomization approaches, they find that while many such shared associations...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-01823-w |