Analysis of Co-inhibitory Receptor Expression in COVID-19 Infection Compared to Acute Plasmodium falciparum Malaria: LAG-3 and TIM-3 Correlate With T Cell Activation and Course of Disease

Analysis of Co-inhibitory Receptor Expression in COVID-19 Infection Compared to Acute Plasmodium falciparum Malaria: LAG-3 and TIM-3 Correlate With T Cell Activation and Course of Disease

Coronavirus disease 2019 (COVID-19) which is caused by the novel SARS-CoV-2 virus is a severe flu-like illness which is associated with hyperinflammation and immune dysfunction. The virus induces a strong T and B cell response but little is known about the immune pathology of this viral infection. A...

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Bibliographic Details
Main Authors: Marissa Herrmann, Sophia Schulte, Nils H. Wildner, Melanie Wittner, Thomas Theo Brehm, Michael Ramharter, Robin Woost, Ansgar W. Lohse, Thomas Jacobs, Julian Schulze zur Wiesch
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
COVID-19
malaria
SARS-CoV-2
Plasmodium falciparum
T cells
PD-1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01870/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01870/full

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