Identification of two Wnt-responsive elements in the intron of RING finger protein 43 (RNF43) gene.

RING finger protein 43 (RNF43), an E3-type ubiquitin ligase, is frequently up-regulated in human colorectal cancer. It has been shown that expression of RNF43 is regulated by the Wnt-signaling pathway. However the regulatory region(s) for its transcriptional activation has not been clarified. In thi...

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Bibliographic Details
Main Authors: Norihiko Takahashi, Kiyoshi Yamaguchi, Tsuneo Ikenoue, Tomoaki Fujii, Yoichi Furukawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24466159/pdf/?tool=EBI