Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

Infection of mice with Citrobacter rodentium is a common model of infection with attaching-and-effacing pathogens. Here, Connolly et al. analyse the transcriptome of C. rodentium during mouse infection, showing host-induced coordinated upregulation of virulence factors and 1,2-propanediol metabolism...

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Bibliographic Details
Main Authors: James P. R. Connolly, Sabrina L. Slater, Nicky O’Boyle, Robert J. Goldstone, Valerie F. Crepin, David Ruano-Gallego, Pawel Herzyk, David G. E. Smith, Gillian R. Douce, Gad Frankel, Andrew J. Roe
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06701-4

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https://doi.org/10.1038/s41467-018-06701-4

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