Neuronal Differentiation from Induced Pluripotent Stem Cell-Derived Neurospheres by the Application of Oxidized Alginate-Gelatin-Laminin Hydrogels

Neuronal Differentiation from Induced Pluripotent Stem Cell-Derived Neurospheres by the Application of Oxidized Alginate-Gelatin-Laminin Hydrogels

Biodegradable hydrogels that promote stem cell differentiation into neurons in three dimensions (3D) are highly desired in biomedical research to study drug neurotoxicity or to yield cell-containing biomaterials for neuronal tissue repair. Here, we demonstrate that oxidized alginate-gelatin-laminin...

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Bibliographic Details
Main Authors: Thomas Distler, Ines Lauria, Rainer Detsch, Clemens M. Sauter, Farina Bendt, Julia Kapr, Stephan Rütten, Aldo R. Boccaccini, Ellen Fritsche
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomedicines
Subjects:
oxidized alginate
laminin
hydrogels
human induced pluripotent stem cells (hiPSC)
neurospheres
tissue engineering
Online Access:https://www.mdpi.com/2227-9059/9/3/261

Internet

https://www.mdpi.com/2227-9059/9/3/261

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