A Chronic Ocular-Hypertensive Rat Model induced by Injection of the Sclerosant Agent Polidocanol in the Aqueous Humor Outflow Pathway

A Chronic Ocular-Hypertensive Rat Model induced by Injection of the Sclerosant Agent Polidocanol in the Aqueous Humor Outflow Pathway

Background: To induce a moderate chronic ocular hypertension (OHT) by injecting polidocanol, a foamed sclerosant drug, in the aqueous humor outflow pathway. Methods: Intraocular pressure (IOP) was monitored for up to 6 months. Pattern and full-field electroretinogram (PERG and ERG) were recorded and...

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Bibliographic Details
Main Authors: Román Blanco, Gema Martinez-Navarrete, Consuelo Pérez-Rico, Francisco J. Valiente-Soriano, Marcelino Avilés-Trigueros, Javier Vicente, Eduardo Fernandez, Manuel Vidal-Sanz, Pedro de la Villa
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
chronic ocular hypertension
optical coherence tomography
pattern and full-field electroretinogram
polidocanol injection
rat glaucoma model
Online Access:https://www.mdpi.com/1422-0067/20/13/3209

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https://www.mdpi.com/1422-0067/20/13/3209

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