Role of G2-S16 Polyanionic Carbosilane Dendrimer in the Prevention of Respiratory Syncytial Virus Infection In Vitro and In Vivo in Mice

The respiratory syncytial virus (RSV) causes respiratory infection and bronchiolitis, requiring hospitalization mainly in infants. The interaction between RSV, envelope glycoproteins G and F, and cell surface heparan sulfate proteoglycans (HSPG) is required for binding and entry into the host cells....

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Bibliographic Details
Main Authors: Ignacio Rodriguez-Izquierdo, Rafael Ceña-Diez, Maria Jesús Serramia, Rosa Rodriguez-Fernández, Isidoro Martínez, Mariángeles Muñoz-Fernández
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/13/13/2141