Lgr5-Positive Supporting Cells Generate New Hair Cells in the Postnatal Cochlea

The prevalence of hearing loss after damage to the mammalian cochlea has been thought to be due to a lack of spontaneous regeneration of hair cells, the primary receptor cells for sound. Here, we show that supporting cells, which surround hair cells in the normal cochlear epithelium, differentiate i...

Full description

Bibliographic Details
Main Authors: Naomi F. Bramhall, Fuxin Shi, Katrin Arnold, Konrad Hochedlinger, Albert S.B. Edge
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114000253