The chemokine fractalkine (CX3CL1) attenuates H2O2-induced demyelination in cerebellar slices

The chemokine fractalkine (CX3CL1) attenuates H2O2-induced demyelination in cerebellar slices

Abstract Background Fractalkine/CX3CR1 signalling has been implicated in many neurodegenerative and neurological diseases of the central nervous system (CNS). This signalling pathway plays an important role in regulating reactive oxygen species (ROS), as well as itself being altered in conditions of...

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Bibliographic Details
Main Authors: Sinead A. O’Sullivan, Kumlesh K. Dev
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Journal of Neuroinflammation
Subjects:
Fractalkine
CX3CL1
GOX-CAT
Hydrogen peroxide
demyelination
Online Access:http://link.springer.com/article/10.1186/s12974-017-0932-4

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http://link.springer.com/article/10.1186/s12974-017-0932-4

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