Pulmonary Toxicity, Distribution, and Clearance of Intratracheally Instilled Silicon Nanowires in Rats

Silicon nanowires (Si NWs) are being manufactured for use as sensors and transistors for circuit applications. The goal was to assess pulmonary toxicity and fate of Si NW using an in vivo experimental model. Male Sprague-Dawley rats were intratracheally instilled with 10, 25, 50, 100, or 250 μg of...

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Bibliographic Details
Main Authors: Jenny R. Roberts, Robert R. Mercer, Rebecca S. Chapman, Guy M. Cohen, Sarunya Bangsaruntip, Diane Schwegler-Berry, James F. Scabilloni, Vincent Castranova, James M. Antonini, Stephen S. Leonard
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2012/398302