The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata

The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata

To thrive in the acidic vaginal tract, Candida glabrata has to cope with high concentrations of acetic acid. The mechanisms underlying C. glabrata tolerance to acetic acid at low pH remain largely uncharacterized. In this work, the essential role of the CgHaa1 transcription factor (encoded by ORF CA...

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Bibliographic Details
Main Authors: Ruben T. Bernardo, Diana V. Cunha, Can Wang, Leonel Pereira, Sónia Silva, Sara B. Salazar, Markus S. Schröder, Michiyo Okamoto, Azusa Takahashi-Nakaguchi, Hiroji Chibana, Toshihiro Aoyama, Isabel Sá-Correia, Joana Azeredo, Geraldine Butler, Nuno Pereira Mira
Format: Article
Language:English
Published: Oxford University Press 2017-01-01
Series:G3: Genes, Genomes, Genetics
Subjects:
CgHaa1
acetic acid
Candida glabrata
vaginal dysbiosis
vaginal candidiasis
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.034660

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http://g3journal.org/lookup/doi/10.1534/g3.116.034660

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