A microfluidics platform for combinatorial drug screening on cancer biopsies

Cancer patients exhibit specific sensitivities toward drug combinations that cannot be easily predicted. Here the authors setup a microfluidic platform that allows testing of multiple drug combinations correctly predicting sensitivity in vivo and they use it on patients biopsies to define effective...

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Bibliographic Details
Main Authors: Federica Eduati, Ramesh Utharala, Dharanija Madhavan, Ulf Peter Neumann, Thomas Longerich, Thorsten Cramer, Julio Saez-Rodriguez, Christoph A. Merten
Format: Article
Published: Nature Publishing Group 2018-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04919-w