Downregulation of long noncoding RNA DLEU1 attenuates hypersensitivity in chronic constriction injury-induced neuropathic pain in rats by targeting miR-133a-3p/SRPK1 axis

Downregulation of long noncoding RNA DLEU1 attenuates hypersensitivity in chronic constriction injury-induced neuropathic pain in rats by targeting miR-133a-3p/SRPK1 axis

Abstract Background Neuropathic pain belongs to chronic pain and is caused by the primary dysfunction of the somatosensory nervous system. Long noncoding RNAs (lncRNAs) have been reported to regulate neuronal functions and play significant roles in neuropathic pain. DLEU1 has been indicated to have...

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Bibliographic Details
Main Authors: Zhen Li, Aiyuan Li, Liping Yan, Tian Yang, Wei Xu, Pengju Fan
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Molecular Medicine
Subjects:
DLEU1
miR-133a-3p
SRPK1
Neuropathic pain
Online Access:http://link.springer.com/article/10.1186/s10020-020-00235-6

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http://link.springer.com/article/10.1186/s10020-020-00235-6

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