Chimeric antigen receptors that trigger phagocytosis

Chimeric antigen receptors that trigger phagocytosis

Chimeric antigen receptors (CARs) are synthetic receptors that reprogram T cells to kill cancer. The success of CAR-T cell therapies highlights the promise of programmed immunity and suggests that applying CAR strategies to other immune cell lineages may be beneficial. Here, we engineered a family o...

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Bibliographic Details
Main Authors: Meghan A Morrissey, Adam P Williamson, Adriana M Steinbach, Edward W Roberts, Nadja Kern, Mark B Headley, Ronald D Vale
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
Chimeric Antigen Receptor
phagocytosis
macrophages
signal transduction
receptors
Fc Receptor
Online Access:https://elifesciences.org/articles/36688

Internet

https://elifesciences.org/articles/36688

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