Pathogenesis of age-related osteoporosis: impaired mechano-responsiveness of bone is not the culprit.

BACKGROUND: According to prevailing understanding, skeletal mechano-responsiveness declines with age and this apparent failure of the mechano-sensory feedback system has been attributed to the gradual bone loss with aging (age-related osteoporosis). The objective of this study was to evaluate whethe...

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Bibliographic Details
Main Authors: Olli V Leppänen, Harri Sievänen, Jarkko Jokihaara, Ilari Pajamäki, Pekka Kannus, Teppo L N Järvinen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2481275?pdf=render