Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing

Nanoparticle Delivery of CRISPR/Cas9 for Genome Editing

The emerging clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated system (Cas) gene-editing system represents a promising tool for genome manipulation. However, its low intracellular delivery efficiency severely compromises its use and potency for clinical applications...

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Bibliographic Details
Main Authors: Li Duan, Kan Ouyang, Xiao Xu, Limei Xu, Caining Wen, Xiaoying Zhou, Zhuan Qin, Zhiyi Xu, Wei Sun, Yujie Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
nanocarriers
CRISPR/Cas9
delivery
exosome
modification
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.673286/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.673286/full

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