Steroid-associated osteonecrosis: Epidemiology, pathophysiology, animal model, prevention, and potential treatments (an overview)

Steroid-associated osteonecrosis (SAON) is a common orthopaedic problem caused by administration of corticosteroids prescribed for many nonorthopaedic medical conditions. We summarised different pathophysiologies of SAON which have adverse effects on multiple systems such as bone marrow stem cells (...

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Bibliographic Details
Main Authors: Xin-Hui Xie, Xin-Luan Wang, Hui-Lin Yang, De-Wei Zhao, Ling Qin
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X14002575