An interaction-based model for neuropsychiatric features of copy-number variants.

Variably expressive copy-number variants (CNVs) are characterized by extensive phenotypic heterogeneity of neuropsychiatric phenotypes. Approaches to identify single causative genes for these phenotypes within each CNV have not been successful. Here, we posit using multiple lines of evidence, includ...

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Bibliographic Details
Main Authors: Matthew Jensen, Santhosh Girirajan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1007879