Generation of human pluripotent stem cell lines with suppressed expression of the Notch ligand DLL4 using short hairpin RNAs

Generation of human pluripotent stem cell lines with suppressed expression of the Notch ligand DLL4 using short hairpin RNAs

Studies with different animal models have shown that the Notch ligand DLL4 has a key role in the development of the embryonic vasculature. Here we describe the generation and characterization of a human embryonic stem cell line and an induced pluripotent stem cell line that constitutively express sh...

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Bibliographic Details
Main Authors: Federico González-Pozas, Rosa Montes, Lourdes López-Onieva, Tamara Romero, Joan Domingo-Reinés, Pedro J. Real, Verónica Ramos-Mejía, Verónica Ayllón
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116300162

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http://www.sciencedirect.com/science/article/pii/S1873506116300162

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