Autophagy-mediated reduction of miR-345 contributes to hepatic cystogenesis in polycystic liver disease

Background & Aims: Polycystic liver disease (PLD) is characterised by increased autophagy and reduced miRNA levels in cholangiocytes. Given that autophagy has been implicated in miRNA regulation, we tested the hypothesis that increased autophagy accounts for miRNA reduction in PLD cholangioc...

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Bibliographic Details
Main Authors: Tatyana Masyuk, Anatoliy Masyuk, Christy Trussoni, Brynn Howard, Jingyi Ding, Bing Huang, Nicholas LaRusso
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:JHEP Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258955592100121X