Synthesis and biological evaluation of 8-substituted berberine derivatives as novel anti-mycobacterial agents
Tuberculosis (TB) is a disease which kills two million people every year and infects over one-third of the world′s population. Eighteen new 8-substituted berberine derivatives were synthesized and evaluated for their anti-mycobacterial activities against Mycobacterium tuberculosis (M. tuberculosis)...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2012-12-01
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| Series: | Acta Pharmaceutica Sinica B |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383512001475 |