Synthesis and biological evaluation of 8-substituted berberine derivatives as novel anti-mycobacterial agents
Tuberculosis (TB) is a disease which kills two million people every year and infects over one-third of the world′s population. Eighteen new 8-substituted berberine derivatives were synthesized and evaluated for their anti-mycobacterial activities against Mycobacterium tuberculosis (M. tuberculosis)...
Main Authors: | Yanxiang Wang, Haigen Fu, Yinghong Li, Jiandong Jiang, Danqing Song |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-12-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383512001475 |
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